BPC-157 + TB-500

A combined lot pairing BPC-157 and TB-500, two of the most frequently studied peptides in tissue and cellular research, supplied together as lyophilized powder for laboratory research use only. Each lot is independently assayed by Janoshik Analytical and the Certificate of Analysis is published before the lot is listed.

Why these two are studied together

BPC-157 and TB-500 appear together in the research literature often enough that a combined preparation is a practical convenience for comparative work. They are structurally unrelated and operate through different proposed mechanisms, which is precisely why investigators examining tissue models frequently run them in parallel rather than in isolation. Supplying them as one lot means a single COA covers both constituents and eliminates cross-lot variability when the two are compared side by side.

BPC-157

BPC-157 is a synthetic pentadecapeptide, fifteen amino acids in length, derived from a partial sequence of body protection compound identified in human gastric juice. It is notable in the literature for unusual stability in aqueous solution relative to many peptides of comparable size.

Published research has examined BPC-157 in the context of angiogenic signaling, growth factor receptor expression, nitric oxide pathway interaction, and fibroblast behavior in culture. Its stability profile and small size make it a common subject in in vitro tissue model work.

TB-500

TB-500 is a synthetic seven-amino-acid fragment corresponding to the actin-binding region of thymosin beta-4, a naturally occurring 43-amino-acid protein found across many tissue types. The fragment reproduces the actin-binding domain of the parent protein without the full-length sequence.

Thymosin beta-4 is one of the principal actin-sequestering proteins in mammalian cells, and research using TB-500 has focused on actin polymerization dynamics, cell migration assays, and cytoskeletal organization. Because it targets cytoskeletal machinery rather than receptor signaling, it provides a mechanistically distinct comparison point alongside BPC-157.

Analytical verification

Every lot is tested by Janoshik Analytical, an independent third-party laboratory, before it is offered for sale. Testing covers identity and purity by HPLC, with mass spectrometry confirming molecular weight for each constituent peptide.

The lot number on your vial label corresponds to a specific Certificate of Analysis in our COA Library. We publish the complete report rather than a headline purity figure. For guidance on interpreting these reports, see how to actually read a Janoshik COA. For background on both compounds, see our article on BPC-157 and TB-500: what the research actually shows.

Specifications

• Constituents: BPC-157 (pentadecapeptide) and TB-500 (thymosin beta-4 fragment)
• Form: Lyophilized powder, sealed vial
• BPC-157 molecular weight: approximately 1419.5 g/mol
• TB-500 molecular weight: approximately 889.0 g/mol
• Purity: See the published COA for the specific lot
• Testing: HPLC and MS by Janoshik Analytical
• Available sizes: 10mg per vial

Handling and storage

Store lyophilized material sealed and protected from light. Short-term storage at 2 to 8 degrees Celsius suits vials in active use; long-term storage at -20 degrees Celsius or below preserves stability over extended periods. Allow sealed vials to equilibrate to room temperature before opening, since condensation introduces moisture that accelerates degradation.

Avoid repeated freeze-thaw cycling, the most common avoidable cause of peptide degradation in laboratory settings. Aliquoting reconstituted material into single-use volumes prevents the full quantity from undergoing repeated temperature transitions. Bacteriostatic water is stocked for laboratories requiring reconstitution diluent.

Related products

Both constituents also appear in our GLOW Blend, which adds GHK-Cu to the same pairing. Browse the full research peptide catalog.

For laboratory research use only. Not for human or veterinary consumption. Not for diagnostic or therapeutic use.